Copyright 1996-2020 Cerner Multum, Inc. This content does not have an English version. Last updated on May 28, 2019. Amiodarone is for use only in treating life-threatening heart rhythm disorders.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Talk to your doctor about the best way to feed your baby during this time. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products.
Tell any doctor who treats you that you are using this medicine.
Select one or more newsletters to continue. If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Subscribe to Drugs.com newsletters for the latest medication news, alerts, new drug approvals and more. Mayo Clinic does not endorse companies or products. Mayo Clinic College of Medicine and Science, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer – Mayo Clinic Health Letter. Do not keep outdated medicine or medicine no longer needed.
Medically reviewed by P. Thornton, DipPharm. fatigue.
Amiodarone affects the rhythm of your heartbeats. Drug information provided by: IBM Micromedex. Many drugs can interact with amiodarone. You may need frequent medical tests while using this medicine and for several months after your last dose. You should not use amiodarone if you have: a serious heart condition called "AV block" (2nd or 3rd degree), unless you have a pacemaker; a history of slow heartbeats that have caused you to faint; or. Keep from freezing.
Grapefruit may interact with amiodarone and lead to unwanted side effects.
The amount of medicine that you take depends on the strength of the medicine. Tell your doctor about all your current medicines and any medicine you start or stop using. Amiodarone drug interactions (in more detail).
Duration of therapy: Until ventricular arrhythmias stabilize (most patients require 48 to 96 hours); maintenance infusion of up to 0.5 mg/min can be continued for up to 3 weeks. Common amiodarone side effects may include: This is not a complete list of side effects and others may occur. This medicine should come with a Medication Guide.
Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To make sure this medicine is safe for you, tell your doctor if you have ever had: an electrolyte imbalance (such as low levels of potassium or magnesium in your blood); or. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Taking amiodarone during pregnancy may harm an unborn baby, or cause thyroid problems or abnormal heartbeats in the baby after it is born.
Call your doctor at once if you have any of these side effects, even if they occur up to several months after you stop using this medicine: wheezing, cough, chest pain, cough with bloody mucus, fever; a new or a worsening irregular heartbeat pattern (fast, slow, or pounding heartbeats); a light-headed feeling, like you might pass out; blurred vision, seeing halos around lights (your eyes may be more sensitive to light); liver problems - nausea, vomiting, stomach pain (upper right side), tiredness, dark urine, jaundice (yellowing of the skin or eyes); nerve problems - loss of coordination, muscle weakness, uncontrolled muscle movement, or a prickly feeling in your hands or lower legs; signs of overactive thyroid - weight loss, thinning hair, feeling hot, increased sweating, tremors, feeling nervous or irritable, irregular menstrual periods, swelling in your neck (goiter); or.
Amiodarone is used to treat ventricular tachycardia or ventricular fibrillation. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. All rights reserved. Missed Dose . -Loading infusions: 150 mg over the first 10 minutes (15 mg/min), followed by 360 mg over the next 6 hours (1 mg/min)
Amiodarone may also affect the child's growth or development (speech, movement, academic skills) later in life. Avoid sunlight or tanning beds.
Maximum dose: Initial infusion rate: 30 mg/min Amiodarone can cause dangerous side effects on your heart, liver, lungs, or vision. Amiodarone can cause dangerous side effects on your heart, liver, lungs, or thyroid. All rights reserved. The most common side effects that can occur with amiodarone oral tablet include: nausea. Follow your doctor's dosing instructions very carefully. Adjustment dose: 600 to 800 mg orally per day for 1 month, then switch to maintenance dose Children—Use and dose must be determined by your doctor. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. An overdose of amiodarone can be fatal. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Store at room temperature away from moisture, heat, and light. Amiodarone could make you sunburn more easily. headache. Take this medicine exactly as directed by your doctor. stomach pain. You may continue to have side effects from this medicine after you stop using it.
signs of underactive thyroid - weight gain, tiredness, depression, trouble concentrating, feeling cold. Do not miss any doses. Storage . Maintenance dose: After the first 24 hours, continue the maintenance infusion rate of 0.5 mg/min; may increase infusion rate to achieve effective arrhythmia suppression. Comments: Mean daily doses greater than 2100 mg for the first 24 hours were associated with increased risk of hypotension. Generic Name: amiodarone tablets (oral) (A mi OH da rone)Brand Names: Pacerone. Not all possible interactions are listed here.
Talk to your doctor before taking any medication during this time. decreased sex drive or performance.
tremor.
This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Drug interactions are possible for up to several months after you stop using amiodarone.
Data sources include IBM Watson Micromedex (updated 1 Oct 2020), Cerner Multum™ (updated 1 Oct 2020), Wolters Kluwer™ (updated 30 Sep 2020) and others.
Call your doctor or get medical help at once if you have: chest pain, fast or pounding heartbeats, trouble breathing, vision problems, upper stomach pain, vomiting, dark urine, jaundice (yellowing of the skin or eyes), or if you cough up blood. Take amiodarone exactly as prescribed by your doctor. Portions of this document last updated: Oct. 01, 2020.
Amiodarone can have long lasting effects on your body. lack of coordination. Use: Initiation of treatment and prophylaxis of frequently recurring VF and hemodynamically unstable VT in patients refractory to other therapy.
Sometimes it is not safe to use certain medications at the same time. https://www.webmd.com/drugs/2/drug-4521/amiodarone-oral/details Overdose symptoms may include weakness, slow heart rate, feeling light-headed, or loss of consciousness. Other brands: Cordarone, Cordarone IV, Nexterone, Pacerone, metoprolol, Rythmol, Calan, Norpace, procainamide, bretylium, InnoPran XL. The dose of this medicine will be different for different patients. If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Call your doctor for medical advice about side effects. if your heart cannot pump blood properly.
Do not double doses. It may take up to 3 weeks before your heart rhythm improves. This medicine can affect the results of certain medical tests. If you need surgery (including laser eye surgery), tell the surgeon ahead of time that you are using amiodarone. -Supplemental infusions: 150 mg over 10 minutes (15 mg/min) for breakthrough episodes of ventricular fibrillation (VF) or hemodynamically unstable ventricular tachycardia (VT) Amiodarone dosage information (in more detail). Check out these best-sellers and special offers on books and newsletters from Mayo Clinic.
-May be administered once a day; twice a day dosing is recommended for total daily doses of 1000 mg or more or in patients who experience gastrointestinal tolerance. This content does not have an Arabic version.
© 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). Loading dose: 800 to 1600 mg orally per day for 1 to 3 weeks (occasionally longer) until adequate arrhythmia control is achieved or if side effects become prominent, then switch to adjustment dose Avoid the use of grapefruit products. This site complies with the HONcode standard for trustworthy health information: verify here. Children—Use and dose must be determined by your doctor. if you have a pacemaker or defibrillator implanted in your chest.
Copyright © 2020 IBM Watson Health. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Avoid driving or hazardous activity until you know how amiodarone will affect you.
-Maintenance dose should be determined according to antiarrhythmic effect as assessed by patient tolerance as well as symptoms, Holter recordings, and/or programmed electrical stimulation; some patients may require up to 600 mg/day while some can be controlled on lower doses. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Advertising revenue supports our not-for-profit mission. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. -Maintenance infusion: 540 mg over the remaining 18 hours (0.5 mg/min)
You may report side effects to FDA at 1-800-FDA-1088. insomnia.
Amiodarone takes a long time to completely clear from your body. You may take the tablets with or without food, but take it the same way each time. We comply with the HONcode standard for trustworthy health information -, Mylan Initiates Voluntary Nationwide Recall of Four Lots of Amiodarone HCl Injection, USP and Tranexamic Acid Injection, USP Due to Carton Label Mix-Up. If your dose is different, do not change it unless your doctor tells you to do so. You will receive your first few doses in a hospital setting, where your heart rhythm can be monitored. Tell your doctor if you have signs of a thyroid problem, such as weight changes, extreme tiredness, dry skin, thinning hair, feeling too hot or too cold, irregular menstrual periods, or swelling in your neck (goiter). Your doctor may occasionally change your dose. Adults—At first, 800 to 1600 milligrams (mg) per day taken in divided doses. Version: 7.01. IV:
Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Skip the missed dose and use your next dose at the regular time. Follow all directions on your prescription label and read all medication guides or instruction sheets. You should not take this medicine if you are allergic to amiodarone or iodine, or if you have heart block, a history of slow heartbeats that have caused you to faint, or if your heart cannot pump blood properly. Amiodarone takes a long time to completely clear from your body. if you have a pacemaker or defibrillator implanted in your chest. Keep using the medicine as directed even if you feel well.
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