Test Code RPR (LAB494) Rapid Plasma Reagin (RPR) Qualitative, Plasma or Serum Performing Laboratory. RPR Qualitative Test. If this test is positive, RPR titer will be performed at an additional charge. She repeated the RPA test a few month later, still coming back reactive at 1:1 . (VDRL) RPR QUALITATIVE- SERUM. SUMMARY OF TEST PRINCIPLE AND CLINICAL RELEVANCE The rapid plasma reagin (RPR) 18-mm circle card test is a macroscopic, nontreponemal flocculation card test used to screen for syphilis (1–4). Syphilis is a sexually transmitted infection (STI) that first causes symptoms seen with many other illnesses. Medical Laboratories of Eastern Iowa. Useful For. Place 50 μl of serum or plasma onto a 18-mm circle of the RPR test card.Using the inverted Dispenstir (closed end) or flat toothpicks, spread the serum or plasma to fill the entire circle. Sequential serologic tests in individual patients should be performed using the same testing method (VDRL or RPR), preferably by the same laboratory. It is a blood test, which is conducted to identify syphilis, which is an STD or a sexually transmitted disease.How to prepare for the test?No special preparation is needed for this test. RPR test is short for rapid plasma reagin test, is a screening test for syphilis. The rapid plasma reagin test (RPR test or RPR titer) is a type of rapid diagnostic test that looks for non-specific antibodies in the blood of the patient that may indicate an infection by syphilis or related non-venereal treponematoses.It is one of several nontreponemal tests for syphilis (along with the Wassermann test and the VDRL test).The term reagin means that this test does not … The infection is systemic and the disease is SUMMARY AND EXPLANATION RPR test measures substances (proteins) called antibodies that are present in the blood of people who may have syphilis. A negative (nonreactive) RPR is compatible with a person not having syphilis, but in the early stages of the disease, the RPR often gives false negative results. ... Nontreponemal test results are reported with a qualitative result and a quantitative titer, which usually correlates with disease activity 20). The VDRL and RPR are equally valid assays, but quantitative results from the two tests cannot be compared directly because RPR titers frequently are slightly higher than VDRL titers. Specimen Requirements. Early symptoms include rash, fever, swollen glands, muscle aches, and sore throat. INTENDED USE The Macro-Vue™ RPR (Rapid Plasma Reagin) 18 mm Circle Card Test is a nontreponemal testing procedure for the serologic detection of syphilis.1, 2 II. The rapid plasma reagin (RPR) test is a blood test that looks for antibodies to syphilis. Only Recently this year her RPR came back reactive at 1:1 . 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